Greenherb supplies a premium, scientifically-validated Danshen Extract, derived from the dried scarlet red roots of Salvia miltiorrhiza Bunge, a cornerstone herb in Traditional Chinese Medicine known for its profound ability to activate blood circulation and alleviate blood stasis without compromising vital Qi. Our danshen root extract is meticulously processed to preserve the full spectrum of bioactive compounds, including lipophilic tanshinones (Tanshinone IIA, Cryptotanshinone) and hydrophilic phenolic acids (Salvianolic Acid B, Danshensu). This potent danshen powder delivers clinically-supported benefits for cardiovascular wellness, blood circulation, and heart health, offering a time-honored botanical with extensive modern scientific validation for global nutraceutical, dietary supplement, and pharmaceutical markets.
We support global B2B customers with consistent quality, scalable supply, and comprehensive analytical documentation, enabling the development of evidence-based products that leverage this legendary "red sage" root's remarkable therapeutic versatility.
Dual-Active Bioavailability Strategy – Our danshen extract preserves the complementary actions of both lipophilic tanshinones (Tanshinone IIA, Cryptotanshinone) and hydrophilic phenolic acids (Salvianolic Acid B, Danshensu). Research indicates that tanshinones act at an early stage after ischemic injury by inhibiting intracellular calcium and cell adhesion pathways, while salvianolic acid acts by down-regulating apoptosis, demonstrating significant mechanistic and temporal differences between the two compound classes.
Clinically-Validated Cardiovascular & Heart Health – Multiple clinical studies and reviews confirm that danshen extract and its components possess broad cardiovascular protective actions, including anti-atherosclerotic, anti-arrhythmic, anti-thrombotic, anti-hypertensive, and anti-myocardial ischemia-reperfusion injury effects. Since 2000, 39 clinical trials have been identified using Salvia miltiorrhiza in TCM prescriptions for treating patients with cardiovascular disease.
Effective Support for Stable Angina & Coronary Artery Disease – A 2025 randomized controlled trial demonstrated that Fufang Danshen administration significantly reduced circulating triglyceride levels (P=0.013) and decreased the frequency of angina episodes (P=0.021) in patients with stable coronary heart disease. Five Danshen-based preparations have shown clinical improvement rates of 72.4%–91.6% and ECG improvement rates of 54.5%–71.6% for stable angina treatment.
Potent Antioxidant & Anti-Inflammatory Protection – The tanshinones and salvianolic acids in our danshen root extract provide powerful free radical scavenging activity, protecting cells from oxidative stress, reducing inflammation, and supporting endothelial function through multiple pathways.
Rich in Over 300 Bioactive Chemical Components – To date, more than 318 chemical compounds have been isolated and identified from Salvia miltiorrhiza, including diterpenoid quinones, phenolic acids, triterpenes, flavonoids, and saccharides, which work synergistically to deliver comprehensive therapeutic benefits.
Traditional Meridian & Blood-Moving Legacy – Danshen is classified within the heart and liver meridians and is renowned for its ability to activate collaterals and blood vessels, facilitate the removal of blood stasis, and promote blood circulation. Clinically, it has been used traditionally to treat uterine bleeding, irregular menstruation, blood stasis, abdominal pain, and insomnia.
Sustainably Sourced from Mature Roots – Our danshen extract is sourced from mature Salvia miltiorrhiza roots harvested in autumn from certified cultivation regions in China, ensuring optimal bioactive compound development and sustainable agricultural practices.
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Item |
Specification |
Test result |
|
Danshen Extract |
10:1 |
Conforms |
|
Physical Control |
||
|
Appearance |
Brown yellow powder |
Conforms |
|
Odor & Taste |
Characteristic |
Conforms |
|
Identification |
Positive |
Conforms |
|
Part Used |
Root |
Conforms |
|
Loss on Drying |
≤5.0% |
Conforms |
|
Ash |
≤5.0% |
Conforms |
|
Particle size |
NLT 95% through 80 mesh |
Conforms |
|
Solubility |
Water soluble |
Conforms |
|
Allergens |
None |
Conforms |
|
Chemical Control |
||
|
Heavy Metals |
NMT10ppm |
Conforms |
|
Lead(Pb) |
NMT2ppm |
Conforms |
|
Arsenic (As) |
NMT1ppm |
Conforms |
|
Mercury(Hg) |
NMT1ppm |
Conforms |
|
Cadmium(Cd) |
NMT1ppm |
Conforms |
|
GMO Status |
GMO Free |
Conforms |
|
Microbiological Control |
||
|
Total Plate Count |
10,000cfu/g Max |
Conforms |
|
Yeast & Mold |
1,000cfu/g Max |
Conforms |
|
E.Coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
Greenherb's Danshen Extract captures the therapeutic essence of a herb that has been called a "prospective healing sage" in Traditional Chinese Medicine for centuries. Known in China as the "red root" for its vivid scarlet hue, danshen has been used for hundreds of years to treat numerous ailments, particularly cardiovascular diseases, and is considered one of the most important TCM herbs in clinical practice. Modern science has now validated this ancient wisdom, revealing that over 318 individual compounds isolated from the root exhibit a wide range of pharmacological effects, including anti-atherosclerotic, anti-thrombotic, anti-inflammatory, neuroprotective, and anti-fibrotic activities. What makes danshen truly remarkable is its dual-compound strategy: lipophilic tanshinones target early-stage ischemic injury, while hydrophilic salvianolic acids protect against later apoptotic damage, providing comprehensive cardioprotection through complementary mechanisms. Our danshen extract powder delivers these benefits in a consistent, concentrated form, making it the ideal choice for brands developing advanced products in the cardiovascular wellness, blood circulation support, and heart health categories. Whether you need a danshen supplement for heart health or pure danshen powder for cardiovascular formulations, our ingredient provides the clinical credibility that today's discerning brands demand.
Botanical Source: Salvia miltiorrhiza Bunge (Danshen, Red Sage)
Used Part: Dried Root and Rhizome (harvested in autumn)
Key Active Components: Lipophilic Diterpenoid Quinones (Tanshinone IIA, Cryptotanshinone, Tanshinone I, Dihydrotanshinone), Hydrophilic Phenolic Acids (Salvianolic Acid B, Danshensu, Protocatechuic Aldehyde, Rosmarinic Acid) .
Standardization: Available standardized to Tanshinone IIA (2%, 5%, 10%), Salvianolic Acid B (5%, 10%), or total phenolic acids .
Appearance: Fine, scarlet red to reddish-brown powder with characteristic aromatic, slightly bitter odor
Flavor: Bitter, slightly astringent, with typical danshen notes
Solubility: Water-soluble and alcohol-soluble extract options available to capture both lipophilic and hydrophilic fractions
Detection Method: HPLC (High-Performance Liquid Chromatography)
Our process is optimized to preserve both the delicate lipophilic tanshinones and the hydrophilic phenolic acids:
Sustainable Cultivation & Harvest: Salvia miltiorrhiza is cultivated in certified growing regions and harvested in autumn when root bioactive content is at its peak. Mature roots (typically 3-4 years growth) are selected for optimal compound concentration.
Cleaning & Drying: Roots are thoroughly washed, sorted, and gently dried at low temperatures to preserve both lipophilic and hydrophilic compounds.
Size Reduction: Dried roots are milled to a uniform particle size to optimize extraction efficiency.
Dual-Extraction Process: Utilizes optimized ethanol-water extraction to efficiently extract both lipophilic tanshinones and hydrophilic phenolic acids. This approach captures the full synergistic profile of the root's bioactive compounds.
Filtration & Concentration: The crude extract is filtered to remove insoluble plant material and concentrated under vacuum at low temperatures.
Purification & Standardization: The concentrated extract undergoes purification to enrich specific bioactive fractions to the desired specification. HPLC analysis guides blending to achieve guaranteed, consistent marker levels .
Spray Drying: The standardized liquid is spray-dried into a fine, free-flowing danshen extract powder using gentle processing conditions.
Comprehensive Quality Verification: Each batch undergoes rigorous HPLC analysis for Tanshinone IIA, Salvianolic Acid B, and other marker compounds, along with testing for heavy metals, microbial safety, and residual solvents.
Danshen Extract is utilized for its scientifically-documented, multi-system health benefits:
Supports Cardiovascular Health & Blood Circulation*: Danshen extract improves coronary artery blood flow, dilates blood vessels, enhances microcirculation, and reduces blood viscosity. It demonstrates cardioprotective properties beneficial for angina, myocardial infarction, and other heart conditions. The administration of danshen has been shown to effectively reduce circulating triglyceride levels and decrease the frequency of angina episodes in patients with stable coronary heart disease.
Provides Potent Antioxidant & Anti-Inflammatory Protection*: The tanshinones and salvianolic acids provide powerful free radical scavenging activity, protecting cells from oxidative stress and reducing inflammation. These properties help protect cells from oxidative damage and contribute to overall health and disease prevention.
Supports Healthy Platelet Function & Blood Flow*: Danshen components inhibit ADP-induced platelet aggregation and synthesis of vasoconstrictive substances, supporting healthy blood flow and reducing the risk of abnormal clot formation.
Promotes Endothelial & Vascular Health*: Accumulating evidence suggests that danshen and its components prevent vascular diseases, in particular atherosclerosis and cardiac diseases, including myocardial infarction, myocardial ischemia/reperfusion injury, arrhythmia, cardiac hypertrophy and cardiac fibrosis.
Supports Neuroprotective & Cognitive Health*: Preclinical research indicates that danshen may have neuroprotective properties, potentially benefiting conditions like Alzheimer's disease and other neurodegenerative disorders. It may help improve cognitive function and protect against neuronal damage.
Supports Liver & Organ Health*: Danshen is used to support liver health, helping protect liver cells from damage, reduce liver inflammation, and improve liver function. It also demonstrates anti-renal fibrotic and anti-pulmonary fibrotic effects.
Offers Broad Therapeutic Potential*: Crude extracts and pure compounds isolated from danshen exhibit a wide range of pharmacological effects, including anti-depressive, sedative and analgesic, anti-diabetic, and anti-tumor activities.
Danshen Extract is a versatile ingredient across multiple product categories:
Dietary Supplements
Cardiovascular health and heart support capsules/tablets
Blood circulation and microcirculation enhancement products
Antioxidant and anti-inflammatory formulations
Healthy aging and cognitive support complexes
Liver health and detoxification supplements
Pharmaceutical & Clinical Applications
Standardized danshen extract for professional-grade cardiovascular products
Ingredient in compound herbal formulations for heart health
Functional Foods & Beverages
Heart-healthy functional drinks and wellness shots
Herbal tea blends and tonic formulations
Nutritional supplements for circulatory support
Traditional & Herbal Formulations
Key ingredient in Traditional Chinese Medicine formulas for blood stasis and heart health
Component in practitioner-grade herbal blends for cardiovascular and gynecological support
Cosmetic & Personal Care
Antioxidant-rich serums and creams for skin health
Natural ingredient in anti-aging and protective formulations
Greenherb is your trusted partner for premium, scientifically-validated danshen extract. Whether you need danshen root extract for cardiovascular health formulations, high-quality danshen powder for blood circulation support, or a reliable danshen supplement ingredient for heart health capsules, we provide the purity, potency, and documentation needed for successful product development in global nutraceutical and pharmaceutical markets. Our danshen extract powder is available in multiple standardization levels to suit your specific formulation requirements—from danshen root extract powder for dietary supplements to concentrated danshen extract for advanced cardiovascular products.
Contact us today to discuss your needs, request samples and analytical data, or receive a detailed quote for your project.
Greenherb — delivering the clinically-proven heart health wisdom of the "red sage" root in modern standardized form.
