Greenherb supplies a premium, standardized Coleus Forskohlii Extract, derived from the roots of Plectranthus barbatus (syn. Coleus forskohlii), a tropical perennial plant revered in traditional Ayurvedic medicine. Our extract is meticulously processed to concentrate and guarantee consistent levels of its primary bioactive compound, forskolin—a unique diterpene with extensive scientific validation. This potent, versatile ingredient offers a natural solution for weight management, cardiovascular support, and respiratory wellness, providing a clinically-relevant botanical active for global nutraceutical and functional product formulations.
We support customers worldwide with scalable, compliant supply and comprehensive analytical documentation, enabling the development of science-backed products that leverage the exceptional properties of this remarkable botanical.
Standardized for Clinically-Validated Forskolin – Precisely standardized to guaranteed forskolin content (typically 10%, 20%, or higher), ensuring consistent potency and reliable biological activity batch after batch—essential for formulations targeting evidence-based health benefits .
Unique Mechanism: Activates cAMP Pathway – Forskolin directly activates the enzyme adenylate cyclase, increasing intracellular levels of cyclic adenosine monophosphate (cAMP), a critical "second messenger" involved in numerous physiological processes, including fat metabolism, hormone regulation, and cardiovascular function .
Clinically-Supported Weight Management – Human clinical trials have demonstrated that forskolin supplementation may help reduce body fat, increase lean body mass, and support healthy weight management by promoting the release of stored fatty acids from fat cells (lipolysis) .
Supports Cardiovascular & Blood Pressure Health* – By increasing cAMP, forskolin promotes vasodilation (widening of blood vessels), which may help maintain healthy blood pressure already within normal range and support overall cardiovascular function .
Promotes Healthy Inflammatory Balance* – cAMP plays a key role in modulating immune and inflammatory responses; forskolin's ability to elevate cAMP helps support the body's natural ability to manage inflammation .
Respiratory & Bronchial Support* – Traditionally used in Ayurvedic medicine for respiratory conditions, forskolin relaxes bronchial smooth muscle, supporting clear, comfortable breathing and healthy lung function .
Ocular Health Benefits* – Research indicates that forskolin eye drops can help reduce intraocular pressure, offering potential benefits for individuals concerned about glaucoma and overall eye health .
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Specification |
Test result |
|
|
Assay |
Forskolin≥10.0% |
10.10% HPLC |
|
Physical Control |
||
|
Appearance |
Brown yellow powder |
Complies |
|
Characteristic |
Complies |
|
|
Part Used |
Root |
Complies |
|
Loss on Drying |
≤5.0% |
1.36% |
|
Ash |
≤5.0% |
2.38% |
|
Particle size |
95% pass 80 mesh |
Complies |
|
Allergens |
None |
Complies |
|
Chemical Control |
||
|
Heavy metals |
≤10ppm |
Complies |
|
Arsenic (As) |
≤1ppm |
Complies |
|
Mercury(Hg) |
≤0.1ppm |
Complies |
|
Lead (Pb) |
≤3ppm |
Complies |
|
Cadmium(Cd) |
≤1ppm |
Complies |
|
GMO Status |
GMO Free |
Complies |
|
Microbiological Control |
||
|
Total Plate Count |
≤10,000cfu/g |
Complies |
|
Yeast & Mold |
≤1,000cfu/g |
Complies |
|
Coliforms |
Negative |
Negative |
|
E.Coli |
Negative |
Complies |
|
Salmonella sp. |
Negative |
Negative |
Greenherb's Coleus Forskohlii Extract represents a sophisticated convergence of ancient Ayurvedic wisdom and modern molecular pharmacology. The root of this tropical plant has been used for centuries in traditional Indian medicine, but its true potential was unlocked with the discovery of forskolin—a unique diterpene with a direct, well-understood mechanism of action at the cellular level. By activating adenylate cyclase and elevating cAMP, forskolin influences a remarkable range of physiological processes, from fat metabolism to cardiovascular function to inflammatory balance. Our standardized extract delivers this clinically-validated activity in a consistent, reliable form, making it the ideal choice for brands developing advanced products in the weight management, cardiovascular health, sports nutrition, and respiratory wellness categories. For formulators seeking a botanical ingredient with a clear, scientifically-substantiated mode of action, Coleus forskohlii extract offers unparalleled credibility and efficacy.
Botanical Source: Plectranthus barbatus Andrews (syn. Coleus forskohlii Willd.)
Used Part: Root
Primary Active Compound: Forskolin (Coleonol)
Standardization: Typically standardized to 10%, 20%, or 40% Forskolin by HPLC.
Appearance: Fine, light brown to yellowish-brown powder.
Solubility: Forskolin is lipophilic; solubility in water is limited. Often formulated with carriers or in lipid-based delivery systems.
CAS Number: 66575-29-9 (Forskolin)
Our process is optimized to efficiently extract and concentrate the delicate forskolin molecule from the root matrix:
Sustainable Sourcing & Authentication: Sourcing of cultivated Coleus forskohlii roots from trusted agricultural partners, verified for species and quality.
Cleaning & Drying: Roots are thoroughly cleaned, sorted, and carefully dried under controlled, low-temperature conditions to preserve the forskolin content.
Milling & Size Reduction: The dried roots are milled to a uniform particle size to optimize surface area for extraction.
Selective Solvent Extraction: Utilizes food-grade solvents (typically ethyl acetate or ethanol) optimized for efficient extraction of the relatively non-polar forskolin molecule .
Filtration & Concentration: The crude extract is filtered to remove plant debris and concentrated under vacuum at low temperatures to recover solvents and concentrate the active fraction.
Purification & Crystallization: Advanced purification techniques, including column chromatography and crystallization, are employed to enrich the forskolin content to the desired specification (10%, 20%, 40%+).
Drying & Milling: The purified forskolin concentrate is gently dried and milled into a fine, uniform powder, often with a food-grade carrier to ensure consistent flow and potency.
Comprehensive Quality Verification: Each batch undergoes rigorous HPLC analysis to confirm forskolin content, along with testing for residual solvents, heavy metals, and microbial safety.
Coleus Forskohlii Extract is utilized for its well-defined, cAMP-mediated physiological effects:
Supports Weight Management & Body Composition*: Promotes lipolysis (the breakdown of stored fat) by increasing cAMP, which activates hormone-sensitive lipase. Clinical studies have shown reductions in body fat percentage and increases in lean body mass with supplementation .
Supports Cardiovascular & Blood Pressure Health*: Induces vasodilation (widening of blood vessels) through cAMP-mediated relaxation of vascular smooth muscle, helping to maintain healthy blood pressure already within normal range and support overall circulatory function .
Promotes Healthy Inflammatory Balance*: Modulates immune cell activity and the production of pro-inflammatory cytokines through cAMP-dependent pathways, supporting the body's natural ability to manage inflammation .
Supports Respiratory & Bronchial Health*: Relaxes bronchial smooth muscle, promoting clear, comfortable breathing and supporting healthy lung function, consistent with its traditional use in Ayurvedic medicine .
Supports Ocular Health & Intraocular Pressure*: Research indicates that forskolin can help reduce intraocular pressure by decreasing the production of aqueous humor in the eye, offering potential benefits for individuals concerned about glaucoma .
May Support Bone Health*: Preliminary research suggests that cAMP activation may play a role in bone formation and mineral density, though human studies are needed .
Supports Healthy Thyroid Function*: By increasing cAMP, forskolin may help stimulate thyroid hormone release from the thyroid gland, supporting overall metabolic rate .
Coleus Forskohlii Extract is formulated into targeted health and wellness products:
Dietary Supplements
Weight management and fat loss capsules/tablets
Sports nutrition and body composition formulas
Cardiovascular health and blood pressure support products
Respiratory wellness and bronchial support blends
Anti-inflammatory and joint health complexes
Functional Foods & Beverages
Metabolic support and energy-enhancing functional beverages
Weight management smoothie and shake mixes
Wellness shots targeting cardiovascular and metabolic health
Ophthalmic & Specialty Products
Eye health supplements and eye drop formulations (professional use)
Sports Nutrition
Pre-workout formulas for enhanced performance and metabolism
Lean mass and body composition support products
Ayurvedic & Herbal Formulations
Key ingredient in traditional Ayurvedic preparations
Component in modern adaptogenic and metabolic blends
Greenherb is your trusted partner for premium, clinically-validated Coleus Forskohlii Extract. We combine rigorous quality standards with deep expertise in botanical extraction, providing the consistency and documentation needed for successful product development in global nutraceutical markets.
Contact us today to discuss standardization options (10%, 20%, 40% forskolin), request samples and analytical data, or receive a detailed quote for your project.
Greenherb — delivering the science of nature's most uniquely active botanicals.
